Pilsen is a city in the western Czech Republic. It’s known for the Pilsner Urquell Brewery, specializing in bottom-fermented beer since 1842, with brewing cellars and a bottling plant. Ringed by parks, the old center has the 19th-century Great Synagogue, which also hosts concerts. The Cathedral of St. Bartholomew, completed in the 16th century, has Renaissance paintings and a tall spire with a viewing gallery.

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